What are the 6 classes of antiretroviral drugs?

What are the 6 classes of antiretroviral drugs (ARDs) for pediatric HIV infection?

  • Nucleoside or nucleotide reverse transcriptase inhibitors (NRTIs)
  • Nonnucleoside reverse transcriptase inhibitors (NNRTIs)
  • Protease inhibitors (PIs)
  • Integrase inhibitors (IIs)
  • Fusion inhibitors (FIs)
  • Chemokine receptor antagonists (CRAs)

Which are the 5 antiretroviral drugs?

Types of antiretroviral drug

  • abacavir (Ziagen)
  • emtricitabine (Emtriva)
  • lamivudine (Epivir)
  • stavudine (Stavudine)
  • tenofovir disoproxil fumarate (Viread)
  • zidovudine (Retrovir)

What are the three classes of antiviral drugs?

Three classes of antiviral drugs are available for the prevention and/or treatment of influenza: The neuraminidase inhibitors, zanamivir, oseltamivir, and peramivir, which are active against both influenza A and influenza B.

What is the best ARV combination?

Summary of Guidelines for Antiretroviral Therapy for HIV Infection. note: Recommended nucleoside analog combinations are as follows: zidovudine + lamivudine; zidovudine + didanosine; zidovudine + zalcitabine; stavudine + lamivudine; or didanosine + stavudine.

What is CD4 cell count?

A CD4 count is a test that measures the number of CD4 cells in your blood. CD4 cells, also known as T cells, are white blood cells that fight infection and play an important role in your immune system.

How are antivirals classified?

Antiviral drugs can be classified according to their chemical nature (e.g., small-molecules, peptides, biologics) or mechanisms of drug actions against specific viral proteins (e.g., polymerase inhibitors, protease inhibitors, glycoprotein inhibitors).

What is Acriptega?

Acriptega Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).

What is FDC FTC?

The FDC tablet will contain 300 mg tenofovir (TDF), 200 mg emtricitabine (FTC) and 600 mg efavirenz (EFV). This is a significant step forward for SA’s national ARV programme, as it enhances cost-effectiveness and simplifies the first-line regimen.

What is the difference between ARV and art?

HIV drugs are called antiretrovirals (ARVs) because HIV is a type of virus called a retrovirus. ART generally includes three active drugs but a few new options only use two drugs. Some pills contain more than one drug and some pills contain a complete combination (of 2, 3 or 4 drugs).

What does a CD4 count of 400 mean?

The CD4 count doesn’t directly measure HIV. But it is a good surrogate (or indirect) marker for how HIV has damaged your immune system. It can tell indicate the risk of infections. The normal range for a CD4 count in an HIV negative person is between 400 and 1,600. This will cover 19 out of every 20 people (95%).

Is a CD4 count of 600 good?

The CD4 cell count of a person who does not have HIV can be anything between 500 and 1500. People living with HIV who have a CD4 count over 500 are usually in pretty good health. People living with HIV who have a CD4 cell count below 200 are at high risk of developing serious illnesses.

Is antibiotic a drug class?

Most antibiotics fall into their individual antibiotic classes. An antibiotic class is a grouping of different drugs that have similar chemical and pharmacologic properties. Their chemical structures may look comparable, and drugs within the same class may kill the same or related bacteria.

Which is the best classification of antiretroviral agents?

Classification of Antiretroviral Agents 1 NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS. 2 HIV PROTEASE INHIBITORS. HIV protease inhibitors are synthetic antiviral agents… 3 NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS. 4 NUCLEOTIDE REVERSE TRANSCRIPTASE INHIBITORS. 5 HIV FUSION INHIBITORS. HIV fusion inhibitors are synthetic antiviral agents…

Where can I find list of Antiretroviral Guidelines?

Panel on Antiretroviral Guidelines for Adult and Adolescents. U.S. Department of Health and Human Services. U.S. Food and Drug Administration.

Where can I find list of HIV medications?

The HIV medicines are listed according to drug class and identified by generic and brand names. Click on a drug name to view information on the drug from the ClinicalInfo Drug Database . Or download the ClinicalInfo Drug Database app to view the information on your Apple or Android devices.

How is ritonavir used in the treatment of HIV?

*Although ritonavir is a PI, it is generally used as a pharmacokinetic enhancer as recommended in the Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV and the Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection. Fusion inhibitors block HIV from entering the CD4 cells of the immune system.