How effective is letrozole for unexplained infertility?

Rates of conception (defined as having a positive pregnancy test) were 47% in the gonadotropin group, 35% in the clomiphene group, and 28% in the letrozole group. There was no significant difference in the time to conception among the 3 groups.

Can I still get pregnant if I have unexplained infertility?

More than 10 percent of couples trying to conceive are diagnosed with unexplained infertility. This does not mean you will never get pregnant. However, after trying to conceive unsuccessfully for more than a year, it may be in your best interest to pursue treatment to improve your chances.

How successful is IUI with letrozole and trigger shot?

For Patients with Unexplained Infertility Women in this category can expect IUI success rates in the range of 7-10% per cycle. After 3 medicated IUI cycles with Letrozole or Clomid, success rates can range from 15-25%.

How do you beat unexplained infertility?

The principal treatments for unexplained infertility include expectant observation with timed intercourse and lifestyle changes, clomiphene citrate and intrauterine insemination (IUI), controlled ovarian hyperstimulation with IUI, and in vitro fertilization (IVF).

How long does it take to get pregnant with unexplained infertility?

Most couples are able to get pregnant within six months to a year. If you’re unable to conceive after a full year of trying, it’s a good idea to consult a fertility specialist. Sometimes there’s an obvious cause of infertility, like a physical problem with the ovaries, uterus, or testicles.

Can unexplained infertility go away?

The good news for couples with Unexplained Infertility is that fertility treatments help them as well as or better than couples with a known diagnosis. Perhaps the best news for couples with Unexplained Infertility is that the problem often resolves spontaneously.

Is IUI or IVF better for unexplained infertility?

In fact, a large randomized trial on couples with unexplained infertility called FASTT showed definitively that couples who are unsuccessful after 3 cycles of Clomid and intrauterine insemination (IUI) should proceed to IVF as their next treatment.

How can I increase my chances of getting pregnant with unexplained infertility?

Lifestyle changes recommended (like weight loss, quitting smoking) Continue to try on your own (if you’re young and willing) for six months to a year. Clomid or gonadotropins along with IUI for three to six cycles. IVF treatment for three to six cycles.

Is IUI more successful with injectables?

Drug assisted IUI success rates insemination after stimulation with injectable gonadotropins (Follistim, Gonal-F, Bravelle, Menopur). Many studies have shown that IUI plus ovarian stimulation gives a higher success rate than insemination in natural menstrual cycles (no stimulation).

How fast do follicles grow on Femara?

This begins the start of her luteal phase, which is when she can get pregnant. In a Femara (Letrozole) medicated cycle, women ovulate approximately 7-10 days after they begin taking medication. Fertility doctors will start monitoring the patient’s follicle growth after 5-7 days to gauge when she will start ovulating.

Is IVF more successful with unexplained infertility?

Many of our patients with unexplained infertility have very high pregnancy rates with IVF. They generally have healthy sperm and eggs and a normal uterus. So, when the eggs and sperm come together during IVF, it leads to a successful pregnancy.

What to expect when getting injectables with IUI?

Most women don’t experience any side effects from the injectables. Some women will feel breast tenderness, bloating and other mild side effects. IUI itself is no more painful than a normal pelvic exam. Your doctor or a specially trained nurse will insert a speculum in your uterus and expand it.

What is Femara fertility drug used for?

Femara (letrozole) and Clomid Clomiphene Citrate This medication is used to treat infertility in women. (clomiphene) are fertility medications used for stimulating ovulation . Femara is an anti-estrogen drug typically used for treating postmenopausal women with breast cancer. Side effects of Femara and Clomid that are similar include nausea, vomiting, headache, and muscle aches or pains.

When do you ovulate on Femara?

Variable. Most women on Femara ( letrozole ) will ovulate on CD 10 to 16. Hard to predict. Ovulation usually occurs around day 12-16, but it is not always predictable, nor does it always cause ovulation.

Can Femara cause a miscarriage?

A later study was suggestive of the fact that Clomid does thin the uterine lining, but that Femara does not. Femara comes with a lowered risk for miscarriage, too. Doctors are still experimenting with the optimal dose of Femara for its use as a fertility drug.

Does Clomid fertility drug really work?

Clomid is effective at inducing ovulation in women. In fact, when a woman’s only problem is a lack of regular ovulation then many health professionals often recommend the use Clomid. When used correctly, it is believed that you’ll get pregnant within four to six months of beginning your treatment.