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What PPE is required for hazardous drugs?
OSHA’s Personal Protective Equipment (PPE) standard [29 CFR 1910.132] requires employers to provide appropriate PPE (e.g., gloves, goggles, splash aprons) for workers who may handle or be otherwise exposed to hazardous drugs. For more information see OSHA’s Safety and Health Topics page – Personal Protective Equipment.
How do you deactivate hazardous drugs?
The goal of the deactivation step is to render any lingering HD either inactive or inert. By placing a strong oxidizer on the surface and letting the oxidizer degrade the HD, the surface can have all the HD deactivated.
Who should respond to hazardous drug spills?
Whenever possible, spills of LIQUID hazardous drugs will be handled by employees in the area of the spill. Employees may call 911 to contact OESO for telephone advice or assistance cleaning up the spill. OESO will respond to large spills that are beyond the capacity of employees in the vicinity of the spill.
What are the categories of hazardous medications?
DHHS (NIOSH) Publication No. The format for the 2014 list was revised to include three groups of hazardous drugs: (1) Antineoplastic drugs; (2) Non-antineoplastic hazardous drugs; and (3) Drugs with reproductive effects.
What special precautions are required when handling cytotoxic medications?
Clear procedures, which staff who handle cytotoxics or contaminated waste should be familiar with, must be in place for dealing with spillages or contamination of people or work surfaces. Measures to prevent or contain spillages should be used at all times. Any spillages that do occur should be dealt with promptly.
What is the minimum PPE required when compounding hazardous drugs?
Gowns, head, hair, shoe covers, and two pairs of chemotherapy gloves are required for compounding sterile and nonsterile HDs. Two pairs of chemotherapy gloves are required for administering antineoplastic HDs.
Why is USP 800 necessary?
USP General Chapter <800> provides standards for safe handling of hazardous drugs to minimize the risk of exposure to healthcare personnel, patients and the environment.
What are the USP 797 guidelines?
The objective of the USP <797> Standard is to describe conditions and practices to prevent harm, including death, to patients resulting from a contaminated or improperly made compounded sterile preparations (CSPs).
How do you manage cytotoxic spillage?
a) If any part of the skin has been contaminated with cytotoxic drugs, the clothing should be removed and the affected area should be washed immediately with large amounts of soapy water. Seek review by medical team for patients or Occupational Health/ A&E review for staff – as Trust policy.
When would a patient be taken off of hazardous drug precautions?
Call your doctor if you have: Any unexpected or severe side effects such as a rash, bleeding, or a fever of 101° F or 38.3° C or higher. Your skin stays red for more than 1 hour after a spill is washed off.
What is cytotoxic medication used for?
Cytotoxic drugs (sometimes known as antineoplastics) describe a group of medicines that contain chemicals which are toxic to cells, preventing their replication or growth, and so are used to treat cancer. They can also be used to treat a number of other disorders such as rheumatoid arthritis and multiple sclerosis.
Is paliperidone hazardous?
NIOSH has determined it is unlikely that paliperidone (Invega®) poses a carcinogenic, reproductive or developmental hazard to workers in a healthcare setting and is no longer considered a hazardous drug by NIOSH.
How to deal with a spill of cytotoxic drugs?
Cytotoxic Spill Management Procedure The following step is recommended for dealing with cytotoxic spill using a spill kit. a. Notify surrounding personnel of the spill. b. Open the spill kit and display the warning signage while isolating the spill area. c. Prevent the spill from spreading. d.
How was the cytotoxic handling guideline developed?
Methods The guideline was developed primarily from an adaptation and endorsement of an existing guideline and from three systematic reviews. Before publication, the guideline underwent a series of peer and external reviews to gather feedback. All comments were addressed, and the guideline was amended when required.
What do you need to know about handling Cytotoxic waste?
Workers who handle cytotoxic waste receptacles should wear 1 pair of disposable gloves and have a spill kit at their disposal. The waste should travel through as few care units, public areas, and areas containing food or linens as possible (SR). The final storage areas for cytotoxic waste receptacles should be secure.
What should you do if there is spillage in a chemotherapy tray?
If any spillage is noted, or suspected, when cytotoxic drugs are delivered to the ward or clinic, the tray and/or packages must not be touched. Pharmacy should be informed immediately. All patients should be kept away from the site of the spillage.