Contents
What medication is contraindicated with ZOFRAN?
ZOFRAN is contraindicated in patients: known to have hypersensitivity (e.g., anaphylaxis) to ondansetron or any of the components of the formulation [see ADVERSE REACTIONS] receiving concomitant apomorphine due to the risk of profound hypotension and loss of consciousness.
What drug class is ZOFRAN?
Ondansetron is a medicine used to prevent nausea and vomiting caused by surgery or cancer treatments. It’s in a class of medicines called serotonin 5-HT3 receptor antagonists. Ondansetron works by blocking serotonin, a natural substance in the brain that can trigger nausea and vomiting.
Is ZOFRAN a CYP3A4 inhibitor?
In vitro metabolism studies have shown that ondansetron is a substrate for human hepatic cytochrome P-450 enzymes, including CYP1A2, CYP2D6, and CYP3A4. In terms of overall ondansetron turnover, CYP3A4 played the predominant role.
What drugs should not be taken with warfarin?
What drugs, supplements and foods interact with warfarin?
- Aspirin or aspirin-containing products.
- Acetaminophen (Tylenol, others) or acetaminophen-containing products.
- Antacids or laxatives.
- Many antibiotics.
- Antifungal medications, such as fluconazole (Diflucan)
- Cold or allergy medicines.
Who shouldnt take Zofran?
You should not use Zofran if you are allergic to ondansetron or to similar medicines such as dolasetron (Anzemet), granisetron (Kytril), or palonosetron (Aloxi). Zofran orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).
What’s the generic for Zofran?
GENERIC NAME: ONDANSETRON – ORAL (on-DAN-se-tron)
When should you not take Zofran?
Is Zofran considered a narcotic?
Is Zofran (ondansetron) a narcotic? No, Zofran (ondansetron) is not a narcotic, instead it belongs to a class of medication called 5-HT3 (serotonin) receptor antagonist.
Is Zofran a Category B?
The FDA has classified Zofran as a “Pregnancy Category B” drug, meaning that it has not been the subject of any well-controlled studies to determine the effects Zofran may have during pregnancy.
Does warfarin cause nausea?
Warfarin (also known under the brand name Coumadin), a blood thinner that has been around for decades, can trigger a range of side effects. Some of the side effects include nausea, vomiting, diarrhea and abdominal pain. The most common side effect — bleeding — can be life-threatening.
What is the generic name for ondansetron?
Zofran (ondansetron) is an antiemetic and selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting due to cancer chemotherapy and also used to prevent and treat nausea and vomiting after surgery. Zofran is available in generic form.
What are the different strengths of Zofran tablets?
Zofran tablets are oval, film-coated tablets engraved with “Zofran” on one side and are available in the following strengths: 4 mg – white tablet with “4” engraved on the other side. 8 mg – yellow tablet with “8” engraved on the other side.
Are there any side effects to taking Zofran?
Zofran (ondansetron) blocks the actions of chemicals in the body that can trigger nausea and vomiting.
What’s the generic name for the drug Zofran?
Zofran. Generic Name: ondansetron (oral) (on DAN se tron) Brand Name: Zofran, Zofran ODT, Zuplenz. Medically reviewed by Drugs.com. Last updated on Oct 26, 2020. Uses. Warnings. Dosage. What to avoid.
Are there any interactions between Zofran and tramadol?
Although no pharmacokinetic drug interaction between ondansetron and tramadol has been observed, data from 2 small trials indicate that when used together, Zofran may increase patient-controlled administration of tramadol. Monitor patients to ensure adequate pain control when ondansetron is administered with tramadol.