What is the survival rate of uterine leiomyosarcoma?

Leiomyosarcoma

SEER Stage 5-Year Relative Survival Rate
Localized 66%
Regional 34%
Distant 13%
All SEER stages combined 41%

Does anyone survive leiomyosarcoma?

Currently, there is no cure for leiomyosarcoma. The chance for remission is best if the tumor is low grade and is diagnosed at an early stage, but leiomyosarcoma is an aggressive cancer that is often diagnosed at later stages, when it has spread to other parts of the body.

How rare is leiomyosarcoma of the uterus?

Uterine leiomyosarcoma is an extremely rare form of cancer, estimated to occur in 6 out of every 1,000,000 women in the United States each year. The average age at diagnosis is 51. Uterine leiomyosarcomas account for 1-2 percent of all malignant tumors of the uterus. Leiomyosarcoma is a form of soft tissue sarcoma.

How aggressive is uterine sarcoma?

Uterine sarcomas are rare tumors that tend to behave more aggressively and that are associated with a poor prognosis. Diagnosis is usually made following surgical intervention, which often has been performed for benign reasons. The management of uterine sarcomas should employ an interdisciplinary approach.

How fast does uterine sarcoma spread?

It can grow fast and may even double in size in as little as four weeks. The treatment needs to be initiated as soon as possible after its diagnosis.

Does uterine sarcoma require chemotherapy?

Surgery to remove the uterus, sometimes along with the fallopian tubes and ovaries and to check the lymph nodes, is the main treatment for all uterine sarcomas. Sometimes this is followed by treatment with radiation, chemotherapy (chemo), or hormone therapy.

Is sarcoma a death sentence?

Soft tissue sarcomas of the extremities are rare and challenging neoplasms, and every general surgeon is likely to face one at least once or twice in his or her career. Recurrence of extremity sarcoma is not a death sentence, and these patients should be treated aggressively.

Is uterine sarcoma same as leiomyosarcoma?

There are several types of uterine sarcoma. Each type is different in the way it develops and changes over time, as well as in how it should be treated. The types of uterine sarcoma are: leiomyosarcoma.

Is uterine sarcoma the same as leiomyosarcoma?

How fast does leiomyosarcoma grow?

Leiomyosarcoma is a rare but aggressive type of cancer. It can grow fast and may even double in size in as little as four weeks. The treatment needs to be initiated as soon as possible after its diagnosis. Even after the treatment, there are high chances that this type of cancer will recur.

What is leiomyosarcoma of the uterus?

Uterine leiomyosarcoma (LMS) is a rare uterine malignancy that arises from the smooth muscle of the uterine wall. Compared with other types of uterine cancers, LMS is an aggressive tumor associated with a high risk of recurrence and death, regardless of stage at presentation [1].

Where does uterine sarcoma spread to first?

If uterine sarcoma spreads, it tends to first go to places near the uterus. It can spread to the cervix, vagina, ovaries, fallopian tubes, and lymph nodes. In later stages, as it grows, it can spread to the bladder, bowel, lungs, liver, or bone.

What is the recurrence rate of uterine leiomyosarcoma?

Uterine Leiomyosarcoma  Rare malignancy of uterine smooth muscle cells − Comprises 1-2% of all uterine sarcomas − Not derived from uterine fibroids  Aggressive malignancy with poor prognosis and high rate of recurrence − 5 year survival of 40%; minimal if outside the uterus − Recurrence rate of 53-71%

Is it possible to diagnose leiomyosarcoma before surgery?

Presenting symptoms may be vague and mimic other benign uterine conditions. Preoperative diagnosis of leiomyosarcoma is difficult and often only made at time of surgical resection.

What kind of cancer is in the smooth muscle of the uterus?

Uterine leiomyosarcoma (LMS) is a rare uterine malignancy that arises from the smooth muscle of the uterine wall. Compared with other types of uterine cancers, LMS is an aggressive tumor associated with a high risk of recurrence and death, regardless of stage at presentation [ 1 ].

Which is more aggressive LMS or uterine cancer?

Compared with other types of uterine cancers, LMS is an aggressive tumor associated with a high risk of recurrence and death, regardless of stage at presentation [ 1 ]. Tumor grade and other histologic features can influence clinical behavior of the tumors and may be important determinants of treatment recommendations.