- 1 What is one function of the splenic white pulp?
- 2 What is white pulp in spleen?
- 3 Is the red pulp of the spleen expanded?
- 4 Is the spleen a red or white blood cell?
What is one function of the splenic white pulp?
Because of this, the white pulp of the spleen has a very important role in the normal immune response to infection. Antigen presenting cells may enter the white pulp, resulting in activation of the T-lymphocytes stored there.
What is white pulp in spleen?
The spleen contains two main types of tissue – white pulp and red pulp. White pulp is material which is part of the immune system (lymphatic tissue) mainly made up of white blood cells. Red pulp is made up of blood-filled cavities (venous sinuses) and splenic cords.
What causes splenic congestion?
Decreased blood flow The spleen will enlarge if there is a decrease in blood flow through the splenic vein. This may cause spleen congestion and enlargement. This situation may be associated with liver disease and portal hypertension.
What causes white pulp hyperplasia?
The normal white pulp may become diffusely expanded in autoimmune conditions such as rheumatoid arthritis (Felty syndrome), in cytopenic conditions such as thrombotic thrombocytopenic purpura (TTP), immune thrombocytopenic purpura (ITP), and acquired haemolytic anaemia, in viral infections including HIV/AIDS, in other …
How is white pulp formed in spleen?
The splenic parenchyma is made mostly of white and red pulp. White pulp is composed of lymphoid nodules and loose collections of lymphocytes surrounding small arterioles. Red pulp consists of venous spaces into which arteriolar blood empties along with the macrophage-populated structural framework of the spleen.
Where is white pulp?
White pulp is a histological designation for regions of the spleen (named because it appears whiter than the surrounding red pulp on gross section), that encompasses approximately 25% of splenic tissue. White pulp consists entirely of lymphoid tissue.
What is the role of red and white pulp in the spleen?
Its primary function is to filter the blood of antigens, microorganisms, and defective or worn-out red blood cells. The spleen is made of red pulp and white pulp, separated by the marginal zone; 76-79% of a normal spleen is red pulp….
What happens if your spleen ruptures?
A ruptured spleen (a fist-sized organ located in the left upper abdomen) occurs when the surface of this organ is injured, which can lead to internal bleeding. Symptoms include pain in the abdomen and nausea. A ruptured spleen is treated with surgery if the patient has lost a large amount of blood.
What is red pulp of spleen?
The red pulp of the spleen is composed of connective tissue known also as the cords of Billroth and many splenic sinusoids that are engorged with blood, giving it a red color. Its primary function is to filter the blood of antigens, microorganisms, and defective or worn-out red blood cells.
How is white pulp of spleen formed?
What is in the white pulp?
White pulp consists entirely of lymphoid tissue. The marginal zone exists between the white pulp and red pulp. It is located farther away from the central arteriole, in proximity to the red pulp. It contains antigen-presenting cells (APCs), such as dendritic cells and macrophages.
How is the function of the spleen red pulp and white pulp different?
Is the red pulp of the spleen expanded?
The red pulp has a normal vascularity and does not appear to be expanded. No nuclear atypia is apparent. The grossing of the spleen is dealt with in splenectomy grossing . Amyloidosis of the spleen – schematic (pathguy.com).
Is the spleen a red or white blood cell?
Spleen. The spleen is a forgotten organ. Capsule. Red pulp – red blood cells. White pulp – white blood cells. Marginal zone – between red pulp and white pulp. Normal spleen (left) and splenic hamartoma (right).
Is the spleen a forgotten organ of the body?
The spleen is a forgotten organ. Capsule. Red pulp – red blood cells. White pulp – white blood cells. Marginal zone – between red pulp and white pulp. Normal spleen (left) and splenic hamartoma (right). H&E stain. (WC) Sections show unremarkable splenic parenchyma. The nodules of white pulp are well-spaced and have germinal center formation.
What makes the capsule of the spleen white?
Capsule of the spleen is white – resembles sugar-coating. Hyaline material adherent to splenic capsule. Hyaline material = pink acellular crap on a H&E stain. EBV infection.