What happens to the white brain matter when a concussion occurs?

This can cause the brain to bounce around inside the skull. This sudden movement can twist and stretch the cells and nerves in the brain or change how chemicals in the brain work for a short time. When this happens it can change the way the brain is able to send messages to the brain and body.

Can concussions cause white matter in brain?

“White matter damage is definitely prevalent,” Stevens explains. “Virtually all brain trauma patients have it in some form.” They don’t need to suffer severe trauma—people can experience it after a concussion, a fleeting loss of consciousness, he says.

Can concussions cause white matter lesions?

White matter and concussion The athletes who had experienced the most severe symptoms following the concussion were the most likely to display white matter anomalies at the 6-month mark.

Can a head injury cause white matter disease?

White matter injury induces long-term neurological disability after TBI. Acute release of DAMPs activates myeloid cells after TBI.

What does white matter damage do?

White matter damage can cause a great deal of stress and increase the energy demands on the neuron. In some cases, the neuron will not be able to meet the energy demands and the entire neuron will die (cell body, axon, and dendrites). This often starts with retraction of the injured axon.

Can white matter disease cause death?

In general, the prognosis is grave, with the majority of patients dying after a few years. However, some die only after several months, and some manage to survive for several decades [6].

Can white matter in brain heal?

White matter injuries are very serious, but, depending on the type and extent of the injury, extensive recovery may occur. As long as the neuron cell bodies remain healthy, axons can regrow and slowly repair themselves.

What causes white matter injury?

Ischemia-induced inflammation, intrauterine infection, and chorioamnionitis have been proposed as primary causes of white matter injury in the premature infants, all mediated by proinflammatory cytokines.

How long can you live with white matter disease?

It is not possible to stop disease progression, and it is typically fatal within 6 months to 4 years of symptom onset. People with the juvenile form of metachromatic leukodystrophy, which develops between the age of 4 and adolescence, may live for many years after diagnosis.

What does white matter on brain MRI mean?

White matter disease is commonly detected on brain MRI of aging individuals as white matter hyperintensities (WMH), or ‘leukoaraiosis.” Over the years it has become increasingly clear that the presence and extent of WMH is a radiographic marker of small cerebral vessel disease and an important predictor of the life- …

How serious is white matter disease?

Summary: More evidence has been accumulated that damage to cognitive areas is widespread from white matter disease. White matter disease is responsible for about a fifth of all strokes worldwide, more than doubles the future risk of stroke, and is a contributing factor in up to 45% of dementias.

What does white matter on a brain MRI mean?

What are white matter changes in mild traumatic brain injury?

Recent studies of white matter abnormalities at diffusion-tensor imaging in patients with mild TBI have correlated findings with clinical assessment tools of cognitive function, showing complex or widespread patterns of reduced white matter integrity associated with cognitive dysfunction ( 17 ).

What does a concussion do to the brain?

In short, a concussion is a brain injury that changes the way the brain functions. Concussions can happen in a myriad of ways, but contact sports are most commonly to blame.

When do you get a brain scan after a concussion?

The scans and assessments were carried out after 24 hours, 6 days, and 6 months following the trauma. The results of these assessments were compared with 18 matched athletes who had not sustained a head injury. The participants were given advanced brain scans – diffusion tensor imaging and diffusion kurtosis tensor imaging.

What’s the role of white matter in the brain?

Initially considered to be a relatively passive and unimportant part of the brain, white matter is now known to play a vital role in brain function and learning. Gray matter can be thought of as the processing and cognition center, while white matter acts as a relay station, communicating between different areas.