What are the dosage forms of esomeprazole?

Generic name: esomeprazole (oral) (ee so MEP ra zol) Brand name: Esomeprazole Strontium, NexIUM Dosage forms: oral delayed release capsule (20 mg; 40 mg; 49.3 mg); oral delayed release tablet (20 mg); oral powder for reconstitution, delayed release (10 mg; 2.5 mg; 20 mg; 40 mg; 5 mg) Drug class: Proton pump inhibitors

What happens if you take esomeprazole long term?

Esomeprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight. You may be more likely to have a broken bone while taking esomeprazole long term or more than once per day.

How is esomeprazole used in the treatment of Gerd?

Esomeprazole. Prescription esomeprazole is used to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 1 year of age and older.

When to use esomeprazole in combination with amoxicillin?

May be used in conjunction with amoxicillin and clarithromycin (triple therapy) in people with Helicobacter pylori infection and duodenal ulcer disease. Useful in the treatment of hypersecretory conditions such as Zollinger-Ellison syndrome. The dosage of esomeprazole does not need adjusting in people with kidney disease.

When to take esomeprazole before or after sucralfate?

If you are also taking sucralfate, take esomeprazole at least 30 minutes before sucralfate. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Continue to take this medication for the prescribed length of treatment even if you are feeling better.

How to report side effects of esomeprazole in Canada?

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Before taking esomeprazole, tell your doctor or pharmacist if you are allergic to it; or to other PPIs (such as lansoprazole, omeprazole ); or if you have any other allergies.

How is esomeprazole metabolized in the liver?

Esomeprazole is extensively metabolized in the liver by the cytochrome P450 (CYP) enzyme system. The metabolites of esomeprazole lack antisecretory activity. The major part of esomeprazole’s metabolism is dependent upon the CYP2C19 isoenzyme, which forms the hydroxy and desmethyl metabolites.